vaxarray imaging system vx-6000  (InDevR Inc)

Journal: bioRxiv

Article Title: Rapid Identity and Quantity CQA Test for Multivalent mRNA Drug Product Formulations

doi: 10.1101/2022.08.31.506088

Figure Lengend Snippet: (a and b) Schematic of the HA and NA constructs used, respectively, with binding location of oligonucleotide captures shown above each construct. Captures shown in orange were the focus of performance assessment (c) Schematic representation of the VaxArray mRNA microarray slide showing 16 replicate microarrays, (d) individual microarray layout showing 9 replicate spots for each capture oligo, and fiducial markers in grey in top and bottom rows, (e) assay detection schemes represented herein, namely (i) coding region capture and polyT labeling, (ii) coding region capture and 5’ cap labeling, (iii) polyT capture and 5’ cap labeling, (iv) coding region capture and coding region labeling, and (v) polyT capture and coding region labeling.

Article Snippet: Slide(s) were imaged on the VaxArray Imaging System (VX-6000, InDevR Inc.), and downstream data analysis was performed using the VaxArray Analysis Software.

Techniques: Construct, Binding Assay, Microarray, Labeling